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Magnetic resonance imaging was utilized to examine changes in the pars compacta associated with parkinson's disease.We found a reduction in average width of the pars compacta in advanced-but not early-stage patients.Conversely,a significant difference in width(right minus left)was observed in early-but not late-stage patients.Width asymmetry may be a sensitive magnetic resonance imaging indicator for the early detection of Parkinson's disease when there is a predominance of unilateral clinical symptoms. |
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